The role of atrial electro-mechanical coupling as predictor of catheter ablation efficiency: EPs and clinicians working together

Abstract Funding Acknowledgements Type of funding sources: None. Background Atrial fibrillation (AF) results in electrical and structural remodeling the atria, extent has already been found to be associated with higher AF recurrence rate after catheter ablation (CA). Recently, a novel echocardiographic parameter derived from tissue Doppler imaging (TDI), called PA-TDI, introduced assess total atrial activation time, as non-invasive surrogate fibrosis cardiomyopathy. The aim study was investigate role PA-TDI interval predictor efficacy. Methods Consecutive patients persistent or paroxysmal symptomatic referred our Center perform radiofrequency cryoablation procedures were prospectively enrolled. In these patients, complete transthoracic examination performed before procedure, including assessment interval. Results From October 2018 May 2020, 221 consecutive (mean age 61 ± 9 years, 74% male, mean BMI 26.5 3.6, Ejection Fraction 6%) for AF, undergoing procedure (first re-do) Out blanking period, 25% experienced arrhythmia during follow-up 16 months). Compared who did not relapse, have generally longer post-procedural (139.6 22.1 msec vs 153.9 33 msec, respectively). multivariable analysis only post-procedure re-do interventions independent predictors recurrence. A cut-off>144msec identifies at risk post sensitivity 58.7% specificity 73.5% (AUC 0.697). Conclusions is an ablation. This easily obtainable, low-cost, reproducible, accessible even peripheral centers.